Neurodegeneration with Brain Iron Accumulation (NBIA) is a group of rare, genetic, neurological disorders characterized by the progressive degeneration of the nervous system. The common feature among all individuals with NBIA is iron accumulation in the brain, along with a progressive movement disorder. At this time, the exact relationship between genetic causes, iron accumulation and the variable symptoms of NBIA is not fully understood. Similarly, the factors that influence disease severity and rate of progression are still unknown. Sadly, many individuals with NBIA, most frequently children and adolescents, lose the ability to walk, talk, or chew food and become totally dependent on others for all their needs.
In order to halt, reverse or prevent the progression of these rare and often life threatening disorders, it is urgent to promote research that will better the lives of those affected.