PROTEOSTASIS co-organizes this conference in collaboration with EMBO. The meeting organizers are Dr. Ivan Dikic (member of WG2) and Janos Terzic (member of WG2). The co-organizers are Frauke Melchior (member of WG3) and Ron Hay (member of WG3). This meeting centers on Ubiquitin and Ubiquitinlike proteins from molecular mechanisms to human diseases, which are priority thematic in the framework of the Action. Furthermore, it is the Action best interest to establish collaborations with other major programs in order to increase the visibility and impact of the PROTEOSTASIS. This meeting is the top meeting in the field of Ubiquitin in 2015 and it is expected that many members of this COST Action will attend it. In parallel with the EMBO conference and fully integrated in the scientific program, PROSTEOSTASIS will carry out the annual MC and Working Groups Meeting.